Across rheumatic diseases

Predictive value of insulin resistance metabolic score for cardiovascular disease in Chinese arthritis patients: a prospective cohort study

Rheumatology (Oxford)Published Prospective cohort study

Authors' conclusion

METS-IR serves as an effective tool for predicting CVD risk among Chinese patients with arthritis

Study context

Population
Chinese patients with arthritis, China Health and Retirement Longitudinal Study (CHARLS)
Participants
1,059 patients
Exposure
Metabolic Score for Insulin Resistance (METS-IR) quartiles
Outcome
Incident cardiovascular disease (CVD)
Methodological detailsCHARLS data, 7-year follow-up (2011-2018), multivariate Cox regression
  • CHARLS data
  • 7-year follow-up (2011-2018)
  • Multivariate Cox regression

Main finding

As reported in the abstract

Hazard ratio (95% CI)P value
Per quartile increase in METS-IRadjusted for confounding factors
1.36(1.14–1.61)
P < 0.001
Q4vs Q1P for trend < 0.05
1.63(1.12–2.37)
P < 0.05
Significant dose-response relationship
P for trend < 0.05

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Predictive value of insulin resistance metabolic score for cardiovascular disease in Chinese arthritis patients: a prospective cohort study. Rheumatology (Oxford). Published 25 January 2025. doi:10.1093/rheumatology/keaf048

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