Performance of a novel high-resolution infrared thermography marker in detecting and assessing joint inflammation: a comparison with joint ultrasound
Authors' conclusion
HRR showed an excellent performance in the differentiation of joints with US inflammatory activity from non-inflamed joints. Moreover, HRR was able to differentiate between joints with different grades of hypervascularity, making HRR a promising tool to assist disease activity monitoring.
Study context
- Population
- Patients with inflammatory arthritides and healthy controls75 patients · 70 controls
- Participants
- 75 vs 70
- Comparison
- High-resolution infrared thermography marker vs joint ultrasound (US)
- Arthritis-patientsn = 75
- Healthy controlsn = 70reference
- Outcome
- Diagnostic performance of HRR in detecting joint inflammation, with joint US as reference
Methodological detailsjoint US as reference, receiver-operating-characteristics analysis
- Joint US as reference
- Receiver-operating-characteristics analysis
Performance
As reported in the abstract
HRR performance at wrist joints (joint US as reference)
| Test or model | AUC | Sensitivity | Specificity |
|---|---|---|---|
| Hotspot/ROI-Ratio (HRR) | 0.91 (95%CI 0.84-0.98) | 0.83 | 0.88 |
Hotspot/ROI-Ratio (HRR)
AUC0.91 (95%CI 0.84-0.98)
Sensitivity0.83
Specificity0.88
Further findings
HRR values by joint hypervascularity grade
- HRR values statistically different between PDUS I-III vs PDUS 0 and vs healthy subjects for all four joint groups, and in most cases between PDUS I°-III° grades
- P < 0.05
Original publication
Performance of a novel high-resolution infrared thermography marker in detecting and assessing joint inflammation: a comparison with joint ultrasound. Clin Exp Rheumatol. Published 18 December 2023. doi:10.
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