Across rheumatic diseases

Myocardial Performance Index to assess cardiac function in autoimmune connective tissue disease: a systematic review and meta-analysis

Lupus Sci MedPublished Systematic review and meta-analysis

Authors' conclusion

We found elevated MPI values in patients with ACTD compared with healthy controls.

Study context

Population
Autoimmune connective tissue disease (ACTD) patients without cardiovascular abnormalities; studies from 1995 to 202322 studies
Comparison
Autoimmune connective tissue disease vs healthy controls
Outcome
Myocardial Performance Index (MPI), mean differences
Methodological detailsNewcastle-Ottawa Scale quality assessment
  • Newcastle-Ottawa Scale quality assessment

Pooled result

As reported in the abstract

MPI
ACTD vs Healthy controlMD (95% CI)P value
Conventional MPI
0.11(0.08–0.14)
P < 0.00001
Tissue Doppler MPI
0.06(0.03–0.10)
P = 0.00001

Original publication

Myocardial Performance Index to assess cardiac function in autoimmune connective tissue disease: a systematic review and meta-analysis. Lupus Sci Med. Published 20 November 2024. doi:10.1136/lupus-2024-001272

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