Perceptions About Asymptomatic Hyperuricemia and Views About Urate‐Lowering Therapy in People With Asymptomatic Hyperuricemia
Authors' conclusion
Most participants perceived minimal consequences of asymptomatic hyperuricemia. Hyperuricemia was not well understood by participants, and biologic causes were generally underrecognized. Despite a range of concerns about hyperuricemia-associated conditions, particularly kidney disease and cardiovascular disease, a urate-lowering medication for asymptomatic hyperuricemia was not considered necessary
Study context
- Population
- People with asymptomatic hyperuricemia (screening serum urate ≥0.48 mmol/L [8 mg/dL], no current or previous gout symptoms) in a multinational study
- Outcome
- Perceptions about asymptomatic hyperuricemia and views about ULT
Methodological detailsmultinational, questionnaire
- Multinational
- Questionnaire
Main finding
As reported in the abstract
- Did not know the cause of hyperuricemia
- 37%
- Concern about kidney disease or CVD risk higher than concern about elevated serum urate
- P < 0.001
- Medication necessity beliefs most strongly associated with willingness to take ULT (partial R2)
- 0.27, P < 0.001
Observational data: associations, not effects.
Original publication
Perceptions About Asymptomatic Hyperuricemia and Views About Urate‐Lowering Therapy in People With Asymptomatic Hyperuricemia. Arthritis Care Res (Hoboken). Published 26 November 2025. doi:10.
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