Patterns of migration underlie the increasing incidence of Kawasaki disease in Sweden from 1987 to 2018: a cohort study
Authors' conclusion
Our study confirms the age and sex distribution as well as seasonal variation and occurrence of peak years of KD. Migration patterns were associated with increasing numbers of KD
Study context
- Population
- Individuals under the age of 25 diagnosed with Kawasaki disease in Sweden, 1987–2018
- Participants
- 1,917 cases
- Outcome
- Incidence rate of Kawasaki disease
Methodological detailsnationwide Swedish registers, routinely collected administrative and healthcare data
- Nationwide Swedish registers
- Routinely collected administrative and healthcare data
Main finding
As reported in the abstract
Incidence rate per 100 000 under-5-year-olds · 1987–2018
Incidence rate increased over the 32 year period, from
3.6
Incidence rate per 100 000 under-5-year-olds, last 5 years of the study
12.1
95% CI 9.1–15.2
Observational data: associations, not effects.
Further findings
| Outcome | Relative incidence rate (95% CI) |
|---|---|
| Seasonal relative incidence rates (reference: summer)Winter vs Summer | 1.29 (1.14–1.47) |
| Seasonal relative incidence rates (reference: summer)Spring vs Summer | 1.21 (1.07–1.38) |
Age and sex at diagnosis
- Median age at diagnosis, years (IQR 1.47-5.13)
- 2.82
- Males
- 62%
Geographic variation
- Incidence varied geographically across counties, with no discernible pattern
Original publication
Patterns of migration underlie the increasing incidence of Kawasaki disease in Sweden from 1987 to 2018: a cohort study. Scand J Rheumatol. Published 15 July 2026. doi:10.
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