Pain Mechanisms Associated With Disease Activity in Patients With Rheumatoid Arthritis Treated With Disease-Modifying Antirheumatic Drugs: A Regression Tree Analysis
Study context
- Population
- Patients with rheumatoid arthritis (RA) before and after starting a disease-modifying antirheumatic drug (DMARD)
- Participants
- 176 patients
- Exposure
- Groups defined by baseline DAS28 category and knee PPT or conditioned pain modulation (CPM)
- Outcome
- DAS28 after DMARD treatment, predicted by QST modalities (pressure pain thresholds (PPTs), temporal summation, CPM)
- Follow-up
- After DMARD treatment
Methodological detailsregression tree methodology, quantitative sensory testing (QST) before and after starting a DMARD
- Regression tree methodology
- QST before and after starting a DMARD
Main finding
As reported in the abstract
Posttreatment DAS28
Group 1
2.8
mean · SD 1.0
Group 2
3.5
mean · SD 1.0
Group 3
3.4
mean · SD 1.4
Group 4
4.6
mean · SD 1.1
Observational data: associations, not effects.
Original publication
Pain Mechanisms Associated With Disease Activity in Patients With Rheumatoid Arthritis Treated With Disease-Modifying Antirheumatic Drugs: A Regression Tree Analysis. J Rheumatol. Published 15 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →