Osteoarthritis

Osteoarthritis Across Joint Sites in the Million Veteran Program Cohort: Insights From Electronic Health Records and Military Service History

J RheumatolPublished Cohort study

Authors' conclusion

These findings highlight the breadth of factors associated with OA in the MVP veteran population and suggest that physical status may be a modifiable risk factor for OA.

Study context

Population
Veterans in the Million Veteran Program (MVP); Osteoarthritis (OA) defined by ICD-9/10 codes across 3 joints or unspecified
Outcome
Frequency of site-specific OA across 3 joints or unspecified OA by demographics, comorbidities, military service history and physical health
Methodological detailsmultivariable-adjusted models
  • Multivariable-adjusted models

Main finding

As reported in the abstract

OA frequency by demographics, comorbidities and military service
  • Sex- and age-dependent differences in OA frequency (validating previous reports)
  • Unspecified OA associated with higher frequency of 16 Deyo-Charlson comorbidities; associations generally persisted within each joint site-specific OA
  • Prior US Army service associated with higher risk of OA across all joint sites
  • Prior Navy service associated with lower risk of OA across all joint sites; reversed in multivariable-adjusted models (age, sex, ancestry)

Observational data: associations, not effects.

Original publication

Osteoarthritis Across Joint Sites in the Million Veteran Program Cohort: Insights From Electronic Health Records and Military Service History. J Rheumatol. Published 15 September 2024. doi:10.3899/jrheum.2024-0237

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.