Ocular involvement in adult and paediatric patients with monogenic autoinflammatory diseases: a Spanish multicentre retrospective study
Authors' conclusion
Conjunctivitis was the most common ocular manifestation in our TRAPS, FMF, MWS and HIDS patients, and uveitis predominated in Blau syndrome. Severe eye complications and poor visual prognosis were associated with uveitis. Adults with monogenic autoinflammatory diseases seem to exhibit a less severe ophthalmologic presentation than paediatric patients.
Study context
- Population
- Adult and paediatric patients with monogenic autoinflammatory diseases and ocular involvement, Spanish UVESAI cohort44 adults/2 children
- Participants
- 46 participants
- Outcome
- Ophthalmologic manifestations, therapeutic management and visual outcomes
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Ocular manifestations
- Conjunctivitis
- n=26/56.5%
- Uveitis
- n=23/50%
- Structural complications
- Twelve (26.1%)
- Cataracts
- n=11/24%
- Posterior synechiae
- n=10/22%
- Eyes with impaired visual acuity (all with uveitis)
- Seven (8%)
Observational data: associations, not effects.
Original publication
Ocular involvement in adult and paediatric patients with monogenic autoinflammatory diseases: a Spanish multicentre retrospective study. Clin Exp Rheumatol. Published 7 May 2023. doi:10.
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