Autoinflammatory & rare systemic diseases
Occupational, smoking and biomass fuel exposure in a cohort of Mexican patients with IgG4-related disease.
Authors' conclusion
This study shows that there are different patterns of occupational exposure among Mexican IgG4-RD patients, with fewer blue-collar jobs compared to other cohorts.
Study context
- Population
- Mexican patients with IgG4-related disease (IgG4-RD)50.5% male
- Participants
- 95 patients
- Exposure
- White-collar vs blue-collar work
- White-collarn = 63
- Blue-collarn = 15reference
- Outcome
- Work history, occupational exposure, smoking and biomass fuel use
Methodological detailsstandardised questionnaire
- Standardised questionnaire
Main finding
As reported in the abstract
Occupation type
- Paid work
- 78 (82.1%)
- Household work (no paid work)
- 13 (13.7%)
- Students (no paid work)
- 4 (4.2%)
- White-collar vs blue-collar including unpaid household work
- 66.3% vs. 29.5%
- Occupational exposure reported
- 31.6%
Observational data: associations, not effects.
Further findings
Lung involvement
P = 0.02
Biomass exposure
P < 0.001
Occupational exposure and proliferative phenotype
| OR (95% CI) | ||
|---|---|---|
| Occupational exposure | 3.5 (1.08–11.36) | |
| 0.050.21520Odds ratio (log scale) |
Smoking history and lung involvement
| OR (95% CI) | ||
|---|---|---|
| History of smoking | 3.2 (1.1–9.4) | |
| 0.10.31310Odds ratio (log scale) |
Biomass exposure and Mikulicz/systemic phenotype
| OR (95% CI) | ||
|---|---|---|
| Biomass exposure | 2.6 (1.03–6.9) | |
| 0.10.31310Odds ratio (log scale) |
Pancreatobiliary involvement
- Not more frequent among blue-collar workers
Original publication
Occupational, smoking and biomass fuel exposure in a cohort of Mexican patients with IgG4-related disease. Clin Exp Rheumatol. Published 7 July 2024. doi:10. 55563/ clinexprheumatol/ 163s3t
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