Autoinflammatory & rare systemic diseases

Occupational, smoking and biomass fuel exposure in a cohort of Mexican patients with IgG4-related disease.

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

This study shows that there are different patterns of occupational exposure among Mexican IgG4-RD patients, with fewer blue-collar jobs compared to other cohorts.

Study context

Population
Mexican patients with IgG4-related disease (IgG4-RD)50.5% male
Participants
95 patients
Exposure
White-collar vs blue-collar work
  • White-collarn = 63
  • Blue-collarn = 15reference
Outcome
Work history, occupational exposure, smoking and biomass fuel use
Methodological detailsstandardised questionnaire
  • Standardised questionnaire

Main finding

As reported in the abstract

Occupation type
Paid work
78 (82.1%)
Household work (no paid work)
13 (13.7%)
Students (no paid work)
4 (4.2%)
White-collar vs blue-collar including unpaid household work
66.3% vs. 29.5%
Occupational exposure reported
31.6%

Observational data: associations, not effects.

Further findings

Lung involvement

P = 0.02

Biomass exposure

P < 0.001

Occupational exposure and proliferative phenotype

OR (95% CI)
Occupational exposure3.5 (1.08–11.36)

Smoking history and lung involvement

OR (95% CI)
History of smoking3.2 (1.1–9.4)

Biomass exposure and Mikulicz/systemic phenotype

OR (95% CI)
Biomass exposure2.6 (1.03–6.9)

Pancreatobiliary involvement

Not more frequent among blue-collar workers

Original publication

Occupational, smoking and biomass fuel exposure in a cohort of Mexican patients with IgG4-related disease. Clin Exp Rheumatol. Published 7 July 2024. doi:10.55563/clinexprheumatol/163s3t

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