Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status
Authors' conclusion
In this descriptive study, unvaccinated pregnant women with RMD and COVID-19 had a greater number of PTB compared with those fully vaccinated against COVID-19. Additionally, the need for COVID-19 pharmacological treatment was uncommon in pregnant women with RMD regardless of vaccination status.
Study context
- Population
- Pregnant women with rheumatic and musculoskeletal diseases (RMDs) who developed COVID-19 during pregnancy, registry data 24 March 2020–25 February 2022
- Participants
- 73 pregnancies
- Exposure
- Unvaccinated vs one vaccine dose vs two or more doses before COVID-19 in pregnancy
- Unvaccinatedn = 44reference
- One dosen = 3
- Fully vaccinatedn = 26
- Outcome
- Obstetric outcomes by COVID-19 vaccination status
Methodological detailsCOVID-19 Global Rheumatology Alliance registry, stratified by number of vaccine doses before infection
- COVID-19 Global Rheumatology Alliance registry
- Stratified by number of vaccine doses before infection
Main finding
As reported in the abstract
Preterm births
Observational data: associations, not effects.
Further findings
| Outcome | Unvaccinated | Fully vaccinated |
|---|---|---|
| COVID-19 resulted in delivery | 6.8% | 3.8% |
Livebirths among completed pregnancies
- Livebirths of 55 completed pregnancies
- 90.9% (50)
- Ongoing pregnancies
- 24.7% (18)
COVID-19 treatment and hospitalisation (overall)
- No treatment for COVID-19 required
- 83.6% (n = 61)
- Hospital admission required
- 20.5% (n = 15)
Original publication
Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status. Rheumatology (Oxford). Published 19 September 2022. doi:10.
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