OARSI initiative to develop classification criteria for early-stage symptomatic knee OA (early-stage symptomatic knee osteoarthritis (EsSKOA)): What conditions should be considered in the differential diagnosis of EsSKOA?
Authors' conclusion
The differential diagnosis for EsSKOA in adults presenting with undiagnosed knee symptoms includes symptomatic established radiographic knee OA, patellofemoral pain syndrome, meniscal and collateral ligament injuries, and immune-mediated and crystal-induced inflammatory arthritis.
Study context
- Population
- Clinicians consulting monthly on at least five people with undiagnosed knee symptoms7 clinical disciplines
- Participants
- 127 clinicians
- Outcome
- Conditions considered in the differential diagnosis of EsSKOA and among the top three diagnoses for each case scenario
Methodological detailsonline survey of clinicians, case scenarios
- Online survey of clinicians
- Case scenarios
Main finding
As reported in the abstract
Top three conditions in the differential diagnosis
- Knee OA and meniscal injuries among the top three conditions for all three scenarios
- Scenario 1 (40-year-old, 1 month knee stiffness and swelling): followed by immune-mediated and crystal-induced inflammatory arthritis
- Scenario 2 (50-year-old, 8 months knee discomfort while walking): followed by patellofemoral pain syndrome
- Scenario 3 (60-year-old, intense knee discomfort getting out of a car 1 week ago): followed by collateral ligament injuries
Observational data: associations, not effects.
Original publication
OARSI initiative to develop classification criteria for early-stage symptomatic knee OA (EsSKOA): What conditions should be considered in the differential diagnosis of EsSKOA? Osteoarthritis Cartilage. Published 23 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →