Spondyloarthritis & psoriatic arthritis

Non-steroidal anti-inflammatory drugs in psoriatic arthritis: clinical practice suggestions based on scientific evidence and expert opinion.

Clin Exp RheumatolPublished Systematic literature review with Delphi consensus

Authors' conclusion

This study provides a set of indications that may be helpful to the practicing rheumatologist in the prescription of NSAIDs for the relief of the symptoms due to the various clinical manifestations of PsA.

Study context

Population
Patients with psoriatic arthritis (PsA) treated with non-steroidal anti-inflammatory drugs (NSAIDs)7 manuscripts: 5 RCTs, 2 observational
Methodological detailsexpert opinion, Delphi exercise, Medline and Embase, Working group of six rheumatologists and seven methodologists; statements evaluated by multidisciplinary external reviewers via Delphi; literature to 26/1/2022
  • Expert opinion
  • Delphi exercise
  • Medline and Embase
  • Working group of six rheumatologists and seven methodologists; statements evaluated by multidisciplinary external reviewers via Delphi; literature to 26/1/2022

Recommendations

As reported in the abstract

  • RCTs evaluated indomethacin, diclofenac, ibuprofen, nimesulide and celecoxib; studies addressed peripheral joint involvement but not other PsA domains
  • Nimesulide and celecoxib significantly more effective than placebo in controlling joint inflammatory-related symptoms in the short term
  • Working group developed 12 statements on NSAID use in PsA

Original publication

Non-steroidal anti-inflammatory drugs in psoriatic arthritis: clinical practice suggestions based on scientific evidence and expert opinion. Clin Exp Rheumatol. Published 23 August 2024. doi:10.55563/clinexprheumatol/j7b6t5

Composed by AI from the published abstract and checked against it. How Briefs are made →

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