Spondyloarthritis & psoriatic arthritis
Multimorbidity in psoriasis as a risk factor for psoriatic arthritis: a population-based study
Authors' conclusion
Moreover, multimorbidity at psoriasis onset significantly increased the risk of developing PsA
Study context
- Population
- Population-based incidence and prevalence cohorts of psoriasis, Rochester Epidemiology Project
- Participants
- 817 / 1,088 / 1,086
- Exposure
- Psoriasis vs matched comparators without psoriasis; multimorbidity vs none for incident psoriatic arthritis (PsA)
- Incident psoriasisn = 817
- Prevalent psoriasisn = 1,088
- Comparatorsn = 1,086reference
- Outcome
- Development of PsA (ClASsification of Psoriatic ARthritis (CASPAR) criteria) by baseline multimorbidity in psoriasis
Methodological detailspopulation-based, 1:1 matched on age, sex and county, age-, sex- and race-adjusted Cox models
- Population-based
- 1:1 matched on age, sex and county
- Age-, sex- and race-adjusted Cox models
Main finding
As reported in the abstract
Development of PsA in incident psoriasis · median 13.3-year follow-up
Patients developing PsA
23
Cumulative incidence of PsA by 15 years
2.9%
Observational data: associations, not effects.
Further findings
| Outcome | OR |
|---|---|
| Multimorbidity, prevalent psoriasis vs comparatorsPrevalent psoriasis vs Comparators · ≥2 morbidities | 1.35 |
| Multimorbidity, prevalent psoriasis vs comparatorsPrevalent psoriasis vs Comparators · ≥5 morbidities | 1.48 |
Multimorbidity, incident psoriasis vs comparators
- No multimorbidity differences found
Original publication
Multimorbidity in psoriasis as a risk factor for psoriatic arthritis: a population-based study. Rheumatology (Oxford). Published 30 January 2024. doi:10.
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