Systemic sclerosis & Raynaud's
Multicentre retrospective detection of nailfold videocapillaroscopy abnormalities in long covid patients
Authors' conclusion
LC pts show more microvascular alterations at NVC as compared with RC patients and CNT, which may contribute to the pathogenesis of persistent organ/systems dysfunction.
Study context
- Population
- Long covid patients without and with SSc, recovered COVID-19 patients and healthy matched controls who underwent nailfold videocapillaroscopy (NVC), Italian Society of Rheumatology study group
- Participants
- 62 / 24 / 23 / 84
- Exposure
- Long covid without and with SSc vs recovered COVID-19 without long covid vs healthy matched controls
- Non-SSc-LCn = 62
- SSc-LCn = 24
- RCn = 23
- CNTn = 84reference
- Outcome
- NVC abnormalities, non-SSc-LC vs CNT and RC
Methodological detailsnational, healthy matched controls, multivariate analysis, pre- vs post-COVID-19 comparison
- National
- Healthy matched controls
- Multivariate analysis
- Pre- vs post-COVID-19 comparison
Main finding
As reported in the abstract
- Non-SSc-LC vs CNT: P < 0.01, p multivariate<0.01
- Non-SSc-LC vs CNT: P = 0.01, p multivariate<0.05
- Non-SSc-LC vs CNT: P < 0.05, p multivariate<0.05
- Non-SSc-LC vs RC: P < 0.01, p multivariate<0.01
- Non-SSc-LC vs CNT: P < 0.01, p multivariate<0.05
Observational data: associations, not effects.
Further findings
NVC after vs before COVID-19, non-SSc-LC (16 pts)
- More dilated capillaries after COVID-19 vs pre-COVID-19
- P < 0.05
- More microhaemorrhages after COVID-19 vs pre-COVID-19
- P < 0.05
NVC after vs before COVID-19, SSc-LC (24 pts)
- Lower capillary density after COVID-19 vs pre-COVID-19
- P = 0.01
- More dilated capillaries after COVID-19 vs pre-COVID-19
- P < 0.01
Original publication
Multicentre retrospective detection of nailfold videocapillaroscopy abnormalities in long covid patients. RMD Open. Published 28 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →