Across rheumatic diseases

mRNA vaccines in the rheumatologist's future

Semin Arthritis RheumPublished Systematic literature review

Authors' conclusion

A number of mRNA vaccines against viral pathogens are in early to late phase development.

Study context

Population
Clinical and immunologic studies of mRNA vaccines against infectious diseases
Outcome
Status of approved and in-development mRNA vaccines for infectious diseases

Main finding

As reported in the abstract

  • Approved mRNA vaccines include those against SARS CoV-2; immunogenic, good protection against severe disease
  • A number of mRNA influenza vaccines in development, incl. phase 3 studies
  • Others in development target Epstein-Barr Virus (EBV), Cytomegalovirus (CMV), VZV and respiratory syncytial virus (RSV)
  • Many likely to be indicated for immunosuppressed populations, incl. autoimmune inflammatory diseases

Original publication

mRNA vaccines in the rheumatologist's future. Semin Arthritis Rheum. Published 22 November 2023. doi:10.1016/j.semarthrit.2023.152325

Composed by AI from the published abstract and checked against it. How Briefs are made →

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