Metabolic associated fatty liver disease and bone mineral density: a cross-sectional study of the National Health and Nutrition Examination Survey 2017–2018
Authors' conclusion
The present study found that the MAFLD population has higher BMD and a lower risk of osteoporosis than those without MAFLD.
Study context
- Population
- Subjects aged ≥ 50 years from National Health and Nutrition Examination Survey (NHANES) 2017–2018
- Participants
- 817 subjects
- Exposure
- Metabolic associated fatty liver disease (MAFLD) vs non-MAFLD
- MAFLDn = 381
- non-MAFLDn = 436reference
- Outcome
- BMD
Methodological detailsmultivariate linear regression, multiple logistic regression
- Multivariate linear regression
- Multiple logistic regression
Main finding
As reported in the abstract
Femoral BMD
- Participants with MAFLD showed higher femoral bone mineral density (BMDs) than those without MAFLD, especially among males aged ≥ 50 years and females aged ≥ 65 years
Observational data: associations, not effects.
Further findings
Femoral BMD by BMI (subgroup)
- Obese men (BMI ≥ 30 kg/m²) with MAFLD had higher femoral BMDs than controls; trend not present in women
Osteoporosis
- Participants with MAFLD had no increased risks of osteoporosis
Original publication
Metabolic associated fatty liver disease and bone mineral density: a cross-sectional study of the National Health and Nutrition Examination Survey 2017–2018. Osteoporos Int. Published 31 January 2023. doi:10.
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