Spondyloarthritis & psoriatic arthritis
Men with psoriatic arthritis, rheumatoid arthritis and axial spondylarthritis have more children and at an earlier age than matched controls: results from a nationwide cohort
Authors' conclusion
This large nationwide study revealed that men with PsA, RA and axSpA were less childless compared with the general population, a difference that occurred before the onset of the IJD.
Study context
- Population
- Men aged 25–65 years with inflammatory joint disease (Norwegian Arthritis Registry) and matched men without inflammatory joint disease (IJD), Norwaymatched 1:5
- Participants
- 2,649 / 1,716 / 2,766 / 35,655
- Exposure
- Men with psoriatic arthritis (PsA), rheumatoid arthritis (RA) or axial spondylarthritis (axSpA) vs matched men without IJD
- PsAn = 2,649
- RAn = 1,716
- axSpAn = 2,766
- Controlsn = 35,655reference
- Outcome
- Childlessness and number of children per man
Methodological detailsindividually matched 1:5, Information on children from the Medical Birth Registry of Norway
- Individually matched 1:5
- Information on children from the Medical Birth Registry of Norway
Main finding
As reported in the abstract
Childlessness
- In all IJD groups, fewer men were childless vs controls
- p<0.001
Observational data: associations, not effects.
Further findings
Mean number of children per man
- Higher in all diagnostic groups vs controls; difference evident before IJD diagnosis
- P < 0.001
Childlessness, axSpA vs PsA
- axSpA had a slightly higher proportion of childless men vs PsA
- P < 0.001
Age at first fathering
- Men with IJD younger than respective controls when fathering for the first time
- P < 0.001
Original publication
Men with psoriatic arthritis, rheumatoid arthritis and axial spondylarthritis have more children and at an earlier age than matched controls: results from a nationwide cohort. RMD Open. Published 11 August 2025. doi:10. 1136/ rmdopen-2025-005770
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