Inflammatory myopathies

Mediterranean diet and health outcomes in idiopathic inflammatory myopathies

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

Higher MedDiet adherence was associated with more favourable patient-reported physical health, function and symptom burden among individuals with IIM. However, because of the cross-sectional design, the direction and causality of these relationships cannot be determined.

Study context

Population
Adults with self-reported specialist-diagnosed idiopathic inflammatory myopathies (IIM) in the international COVAD survey
Participants
859 adults
Outcome
MedDiet adherence (14-item MEDAS) across IIM subtypes, its predictors, and its association with patient-reported outcomes
Methodological detailsinternational survey, multivariable linear regression, factorial analysis with hierarchical clustering
  • International survey
  • Multivariable linear regression
  • Factorial analysis with hierarchical clustering

Main finding

As reported in the abstract

  • Mediterranean diet (MedDiet) adherence generally modest and varied across subtypes; lowest in IBM
  • Female sex, autoimmune multimorbidity and fewer household members independently associated with higher Mediterranean Diet Adherence Screener (MEDAS) scores
  • Higher MEDAS adherence independently associated with better physical function (PROMIS PF-4), better global physical health (PROMIS GPH), lower disease activity, lower fatigue and lower pain
  • Adjusted outcome models; associations remained significant after adjustment for disease activity, GC exposure, immunosuppressant use, food security and income adequacy

Observational data: associations, not effects.

Original publication

Mediterranean diet and health outcomes in idiopathic inflammatory myopathies. Rheumatology (Oxford). Published 14 August 2026. doi:10.1093/rheumatology/keag424

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