Vasculitis & polymyalgia rheumatica
Measurement Properties of Outcome Instruments for Large-Vessel Vasculitis: A Systematic Literature Review
Authors' conclusion
The ITAS and the DEI-Tak were the instruments with the most adequate measurement properties for disease activity/damage in TA. Disease activity/damage instruments specific to GCA, as well as validated PROs for both GCA and TA, are lacking.
Study context
- Population
- Studies addressing measurement properties of instruments used in giant cell arteritis (GCA) and Takayasu arteritis (TA), published from inception to July 14, 202013 studies
- Outcome
- Measurement properties of outcome instruments used in large-vessel vasculitis (LVV)
Methodological detailsOMERACT and COSMIN frameworks
- OMERACT and COSMIN frameworks
Main finding
As reported in the abstract
Measurement properties of 12 instruments (4 TA-specific, 2 for all systemic vasculitis, 6 non-disease-specific)
- No instruments specific to GCA identified
- ITAS: very good consistency, adequate reliability, doubtful validity for disease activity (TA)
- Disease Extent Index-Takayasu (DEI-Tak): adequate construct validity, doubtful discriminating validity for disease activity/damage (TA)
- Vasculitis Damage Index and BVAS poorly assessed for disease activity/damage
- 6 non-vasculitis-specific patient-reported outcome (PRO) instruments showed inadequate validity in GCA/TA
Original publication
Measurement Properties of Outcome Instruments for Large-Vessel Vasculitis: A Systematic Literature Review. J Rheumatol. Published 1 November 2022. doi:10.
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