Across rheumatic diseases

Longitudinal incidence of native septic arthritis in France: a 13-year analysis of the National Health Data System Database

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

In this nationwide study, we confirmed a slight increase in the incidence of native SA in adults between 2009 and 2022.

Study context

Population
Adults with native septic arthritis (SA) admitted to hospital, French nationwide hospital database (SNDS), 2009–2022; prosthesis joint infection excluded109,160 SA episodes
Outcome
Incidence of native SA over time
Methodological detailsnationwide, longitudinal, 10:1 matching with controls for risk factors
  • Nationwide
  • Longitudinal
  • 10:1 matching with controls for risk factors

Main finding

As reported in the abstract

Incidence rate of native SA (per 100 000 adults per year)

Incidence in 2009

13

Incidence in 2022

16.2

Observational data: associations, not effects.

Further findings

Risk factors of SA (vs matched controls)

OR (95% CI)
RA4.7 (4.5–4.9)
Addiction other than on tobacco or alcohol4.5 (4.3–4.8)
Complicated diabetes4.4 (4.3–4.5)
Dialysis4.0 (3.8–4.3)

All-cause mortality of SA · 1, 6 and 12 months

1 month
3.2%
6 months
8.4%
12 months
11.4%
  • Remained stable during the period

Patient characteristics and microbiology

Men
65%
Mean age (years)
62
Staphylococci (most commonly coded bacteria)
48%

Original publication

Longitudinal incidence of native septic arthritis in France: a 13-year analysis of the National Health Data System Database. Rheumatology (Oxford). Published 10 April 2026. doi:10.1093/rheumatology/keag190

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