Long-term sequelae in patients with spondylodiscitis: independent predictors

Joint Bone SpinePublished Retrospective cohort study

Authors' conclusion

Infectious spondylodiscitis is associated with a high rate of long-term sequelae. Younger age, neurological deficit, elevated ESR, and specific radiological findings, particularly psoas and spinal epidural abscesses, were independent predictors of sequelae.

Study context

Population
Patients hospitalised for infectious spondylodiscitis, 2010–2024
Participants
215 patients
Exposure
Patients with vs without long-term sequelae
  • Sequelaen = 99
Outcome
Independent predictors of long-term sequelae
Methodological detailsmultivariate logistic regression
  • Multivariate logistic regression

Main finding

As reported in the abstract

Independent predictors of long-term sequelae (multivariate analysis)
Age, per year increase (aOR)
0.97; p < 0.01
Elevated erythrocyte sedimentation rate (ESR), per mm/h (aOR)
1.012; p < 0.01
Neurological deficit (aOR)
2.72; p <0.01
Psoas abscess (aOR)
5.27; p<0.001
Spinal epidural abscess (aOR)
2.40; p < 0.05

Observational data: associations, not effects.

Further findings

Age, years · younger with sequelae

P < 0.05

Long-term sequelae (incidence)

Long-term sequelae
99 patients (46%)
Persistent back pain
34.9%
Spinal deformity
14.9%
Radicular pain
6.5%
Highest frequency in tuberculous spondylodiscitis (prevalence differed across etiological groups)
P < 0.05

Original publication

Long-term sequelae in patients with spondylodiscitis: independent predictors. Joint Bone Spine. Published 28 August 2026. doi:10.1016/j.jbspin.2026.106125

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