Lupus & antiphospholipid syndrome

Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspective

RMD OpenPublished Working group perspective

Methodological detailsmulti-partner/disciplinary working group, public-private partnership
  • Multi-partner/disciplinary working group
  • Public-private partnership

Recommendations

As issued by the authors

  1. Need for well-defined severity/refractoriness-based eligibility criteria

  2. Need for long-term monitoring infrastructure

  3. Need for educational and logistical support for rheumatologists and patients

Original publication

Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspective. RMD Open. Published 5 October 2025. doi:10.1136/rmdopen-2025-005866

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