Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) in a Middle Eastern patient cohort
Authors' conclusion
This study showed vast similarities between KD and MIS-C, suggesting that they lie along the same clinical spectrum. However, there are several differences between the two disease entities suggesting that MIS-C most likely represents a new severe variant of KD.
Study context
- Population
- Children with KD or MIS-C, United Arab Emirates, January 2017 to August 2021
- Participants
- 123 children
- Exposure
- KD vs MIS-C
- KDn = 67
- MIS-Cn = 56
- Outcome
- Clinical and laboratory characteristics on admission
- Follow-up
- Admission
Methodological detailsData compared with 87 patients with KD or MIS-C from the literature
- Data compared with 87 patients with KD or MIS-C from the literature
Further findings
Age
P < 0.001
Gastrointestinal manifestations on admission
P < 0.001
Cardiac dysfunction
P < 0.001
Pediatric ICU admission
P < 0.001
White blood cells on admission
P < 0.001
Absolute neutrophils on admission
P 0.008
Absolute lymphocytes on admission
P 0.003
Platelets on admission
P < 0.001
ESR on admission
P < 0.001
ng/mL
| Outcome | KD | MIS-C | P value |
|---|---|---|---|
| Procalcitonin and ferritin (increased in MIS-C) · admission | P < 0.001 | ||
| Procalcitonin | — not stated in the abstract | 2.4 | |
| Ferritin | — not stated in the abstract | 370 |
— not stated in the abstract
Original publication
Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) in a Middle Eastern patient cohort. Pediatr Rheumatol Online J. Published 29 June 2023. doi:10.
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