Pediatric rheumatology

Juvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study

Arthritis Care Res (Hoboken)Published Matched cohort study

Main finding · Annual earningsResult — go to the resultMean annual difference -€736 95% CI -€1,026 to €445

Authors' conclusion

Patients with JIA had lower mean annual earnings and higher work loss than matched general population comparators, but earnings differences diminished in magnitude with age and work loss diminished with calendar period of identification.

Study context

Population
Individuals with juvenile idiopathic arthritis (JIA) identified in the Swedish National Patient Register (2001–2017) and matched general population comparators; earnings and work loss from age 18 yearsmedian 11 years' follow-up
Participants
4,737 vs 23,645
Exposure
JIA vs matched general population comparators
  • JIAn = 4,737
  • Comparatorsn = 23,645reference
Outcome
Earnings and work loss
Methodological detailsnationwide, register-based, individually matched to up to five general population comparators on birth year, sex, and residence county, linear regression adjusted for sex, age, age at identification, calendar year, parental education, work loss and earnings
  • Nationwide
  • Register-based
  • Individually matched to up to five general population comparators on birth year, sex, and residence county
  • Linear regression adjusted for sex, age, age at identification, calendar year, parental education, work loss and earnings

Main finding

Annual earnings · median 11 years' follow-up

Mean annual difference

-€736

95% CI -€1,026 to €445

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeMean difference (days/year) (95% CI)
Work loss · throughout follow-up11 (8–13)

Work loss · throughout follow-up

Difference consistent throughout follow-up; significant effect modification with calendar period of entry (<2005 vs ≥2005), later entry associated with lower work loss

Original publication

Juvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study. Arthritis Care Res (Hoboken). Published 16 March 2025. doi:10.1002/acr.25522

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