Inflammatory myopathies

Increased rates of idiopathic inflammatory myopathies during the COVID-19 pandemic: a single-centre experience

Clin Exp RheumatolPublished Retrospective cohort study

Authors' conclusion

The incidence of IIM increased during the COVID-19 pandemic. These patients display unique features and a more severe presentation. Fortunately, the prognosis remains unchanged.

Study context

Population
Adult patients (>18 years) diagnosed with IIM at the Department of Medicine and Rheumatology Unit of Hadassah Medical Center, Jerusalem, Israel
Participants
18 vs 16
Exposure
IIM diagnosed during COVID-19 vs IIM diagnosed before the outbreak
  • COVID-19n = 18
  • Pre-pandemicn = 16reference
Outcome
Incidence rate of IIM diagnoses (patients/month)
Methodological detailssingle-centre, with literature review
  • Single-centre
  • With literature review

Main finding

As reported in the abstract

IIM incidence rate

Observational data: associations, not effects.

Further findings

Sex distribution in IIM diagnosed during the pandemic

Male predominance (M:F ratio) in IIM patients diagnosed during the pandemic
12:6

Hospitalisation rate (admitted/total patients)

Higher hospitalisation rate, pandemic vs pre-pandemic diagnosis
0.77 vs. 0.43

Patients with CPK >10,000 U/L

Increased number of patients with CPK >10,000 U/L, pandemic vs pre-pandemic diagnosis
3 vs. 1

Survival

Survival comparable between the groups despite more severe presentation and course in the pandemic group

Original publication

Increased rates of idiopathic inflammatory myopathies during the COVID-19 pandemic: a single-centre experience. Clin Exp Rheumatol. Published 13 January 2023. doi:10.55563/clinexprheumatol/970881

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