Efficacy and safety of ultrasound-guided needle muscle biopsy in the diagnosis of idiopathic inflammatory myopathies
Authors' conclusion
Histological analysis was possible in most samples, suggesting that UGNMB is an effective way to collect muscle samples for IIM differential diagnosis.
Study context
- Population
- Patients with suspected inflammatory idiopathic myopathy (IIM) followed up at a Rheumatology Department, January 2022 to April 2024
- Participants
- 44 biopsies
- Outcome
- Adequate samples for histological analysis and establishing an IIM diagnosis
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Biopsy results
Samples allowing thorough histologic evaluation
Nearly 90%
n = 40
Samples compatible with myositis
n = 12
Biopsies with nonspecific muscle changes
27.2%
n = 12
Histological result matching final clinical diagnosis
30 of 44
Observational data: associations, not effects.
Safety
- No moderate or severe adverse events were reported
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Efficacy and safety of ultrasound-guided needle muscle biopsy in the diagnosis of idiopathic inflammatory myopathies. Rheumatology (Oxford). Published 13 May 2025. doi:10.
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