Lupus & antiphospholipid syndrome
Incidence and disease burden of bronchiectasis in systemic lupus erythematosus: a nationwide population-based study in Korea
Main finding · Incidence of bronchiectasis (/100 000 person-years)Result — go to the resultRisk of developing bronchiectasis (fold increase) 1.46 95% CI 1.22–1.76Authors' conclusion
The risk of bronchiectasis was higher in individuals with SLE than in controls, and its development was associated with a worse disease course, higher mortality during follow-up and increased healthcare utilisation.
Study context
- Population
- Adults aged ≥20 years with systemic lupus erythematosus (SLE) diagnosed 2002–2012 and matched controls, Korean National Health Insurance Service datasetmatched cohort
- Exposure
- SLE vs matched controls
- Outcome
- Incident bronchiectasis
Methodological detailsnationwide, 1:4 age, sex and health insurance service-matched
- Nationwide
- 1:4 age, sex and health insurance service-matched
Main finding
As reported in the abstract
Incidence of bronchiectasis (/100 000 person-years) · median follow-up 12.8 years (IQR 10.0-16.0 years)
Risk of developing bronchiectasis (fold increase)
1.46
95% CI 1.22–1.76
By group
SLEvs Matched controls
risk of developing bronchiectasis (fold increase) 1.46 (95% CI 1.22–1.76)
Observational data: associations, not effects.
Further findings
Risk factors for bronchiectasis within the SLE cohort
- Age older than 40 years (highest aHR in those ≥70 years), aHR 25.08, 95% CI 7.62 to 82.53
- Asthma, aHR 1.73, 95% CI 1.11 to 2.70
- Obesity (inverse association), aHR 0.56, 95% CI 0.38 to 0.82
Disease burden in SLE with vs without bronchiectasis
- Significantly higher rates of mortality, ED visits and hospitalisations in those who developed bronchiectasis
Original publication
Incidence and disease burden of bronchiectasis in systemic lupus erythematosus: a nationwide population-based study in Korea. RMD Open. Published 22 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →