High prevalence of diffuse idiopathic skeletal hyperostosis (DISH) among obese young patients – A retrospective observational study

Semin Arthritis RheumPublished Retrospective observational study

Authors' conclusion

The prevalence of DISH among obese young patients was 18 %, which is much higher than in the general population.

Study context

Population
Young (31–50 years) patients with BMI≥35 visiting the bariatric ambulatory clinic of an academic medical center, 2013–2022118 females, 64.2 %
Participants
183 participants
Exposure
DISH vs non-DISH
  • DISHn = 33
Outcome
Prevalence of DISH (Resnick criteria)
Methodological detailssingle academic medical centre, radiographic review
  • Single academic medical centre
  • Radiographic review

Main finding

As reported in the abstract

Prevalence of DISH
Significantly higher than the expected 10 % (Z = 3.62)
p<.001

Observational data: associations, not effects.

Further findings

OutcomeP value
Comorbidities, DISH vs non-DISH (significantly higher prevalence in DISH)DISH vs non-DISHχ2 = 8.30, p<.004
Comorbidities, DISH vs non-DISH (significantly higher prevalence in DISH)DISH vs non-DISHχ2 = 4.69, p<.03
Comorbidities, DISH vs non-DISH (significantly higher prevalence in DISH)DISH vs non-DISHχ2 = 6.16, p<.013
Age, DISH vs non-DISH — Prevalence of DISH increased by age (linear association=14.95) · DISH patients significantly older
P < 0.001 · t = 4.54, p<.001

"Near DISH" (not yet fulfilling the Resnick criteria)

8 patients (4.4 %), 95 % CI 2.2-8.4 %

Original publication

High prevalence of diffuse idiopathic skeletal hyperostosis (DISH) among obese young patients – A retrospective observational study. Semin Arthritis Rheum. Published 22 December 2023. doi:10.1016/j.semarthrit.2023.152356

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