Height loss, back pain and severe pain are highly predictive of pregnancy associated osteoporosis
Authors' conclusion
Height loss, back pain and severity of pain are highly predictive of PAO.
Study context
- Population
- Women with self-reported pregnancy associated osteoporosis (PAO) and pregnant controls, online survey
- Participants
- 225 vs 174
- Comparison
- Women with pregnancy associated osteoporosis vs controls with pregnancies around the same time
- Casesn = 225
- Controlsn = 174reference
- Outcome
- Clinical predictors discriminating PAO cases from controls (ROC analysis)
Methodological detailsonline survey, self-reported diagnosis
- Online survey
- Self-reported diagnosis
Main finding
As reported in the abstract
Clinical features in cases vs controls
Severe pain, sensitivity for PAO
84.2%
95% CI 78.5 to 88.6%
Severe pain, specificity for PAO
98.2%
95% CI 94.6 to 99.5%
Back pain + height loss + severe pain, AUC
0.988
95% CI 0.980 to 0.997
Observational data: associations, not effects.
Further findings
Age, years
Other history features
- Thromboembolic disease, anticoagulant use and family history of osteoporosis more frequent in cases
- Hypertension and pre-eclampsia/eclampsia more frequent in controls
Original publication
Height loss, back pain and severe pain are highly predictive of pregnancy associated osteoporosis. Osteoporos Int. Published 12 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →