Pediatric rheumatology

Heart rate variability (HRV) in juvenile fibromyalgia: a preliminary study

Pediatr Rheumatol Online JPublished Cross-sectional study

Authors' conclusion

Reduced HRV coherence is associated with greater symptom burden and psychological distress in children with JFM.

Study context

Population
Children and adolescents aged 8 to 17 with and without juvenile fibromyalgia2 equal groups
Participants
30 children
Exposure
Children with juvenile fibromyalgia (JFM) vs controls without JFM
Outcome
HRV coherence (emWave Pro)
Methodological detailsobservational, preliminary
  • Observational
  • Preliminary

Main finding

As reported in the abstract

JFM

0.91

mean

Controls

1.27

mean

P < 0.01

Observational data: associations, not effects.

Further findings

OutcomeP value
Pain and anxiety levelsSignificantly higher levels of pain and anxiety in JFMP < 0.001

Correlation of HRV with symptom severity (Widespread Pain Index (WPI), Symptom Severity Scale (SSS)) and anxiety

Inverse correlations between HRV and symptom severity (WPI, SSS) as well as anxiety levels

Original publication

Heart rate variability (HRV) in juvenile fibromyalgia: a preliminary study. Pediatr Rheumatol Online J. Published 12 November 2025. doi:10.1186/s12969-025-01163-7

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