Spondyloarthritis & psoriatic arthritis
A Good Response to Nonsteroidal Antiinflammatory Drugs Does Not Discriminate Patients With Longstanding Axial Spondyloarthritis From Controls With Chronic Back Pain
Authors' conclusion
No major differences in the response to NSAIDs were found between patients with axSpA and those with non-SpA with longstanding chronic back pain.
Study context
- Population
- Consecutive outpatients with chronic back pain (axial spondyloarthritis (axSpA) or non-SpA); previous nonsteroidal antiinflammatory drugs (NSAIDs) withdrawn 2 days before baseline
- Participants
- 233 outpatients
- Exposure
- NSAID response in longstanding axSpA vs non-SpA chronic back pain
- axSpAn = 68
- non-SpAn = 165reference
- Outcome
- Response to NSAIDs: any response (back pain numerical rating scale (NRS) improvement >2 units) and good response (improvement >50%) vs baseline
- Follow-up
- Up to 4 weeks
Methodological detailsconsecutive outpatients, prospective recruitment
- Consecutive outpatients
- Prospective recruitment
Main finding
As reported in the abstract
Any response and good response to NSAIDs
Any response and good response to NSAIDs · up to 4 weeks
Good response
- axSpA vs non-SpA: P value not significant
Observational data: associations, not effects.
Further findings
Rapidity of response and subgroups (demographics, axSpA stages)
- No differences found
Original publication
A Good Response to Nonsteroidal Antiinflammatory Drugs Does Not Discriminate Patients With Longstanding Axial Spondyloarthritis From Controls With Chronic Back Pain. J Rheumatol. Published 15 January 2024. doi:10.
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