Lupus & antiphospholipid syndrome
Global epidemiology of systemic lupus erythematosus: a comprehensive systematic analysis and modelling study
Authors' conclusion
The epidemiology of SLE varies substantially between different sex and age groups and is distributed unequally among geographical regions; specifically, SLE occurs more frequently in high-income countries.
Study context
- Population
- Studies of systemic lupus erythematosus (SLE) incidence and prevalence, global, regional and country-specific112 studies
- Comparison
- Women vs Men
- Outcome
- Global, regional and country-specific incidence and prevalence of SLE
Methodological detailsBayesian hierarchical linear mixed model, four databases searched
- Bayesian hierarchical linear mixed model
- Four databases searched
Pooled result
As reported in the abstract
Global SLE incidence (per 100 000 person-years)
5.14
1.4 to 15.13
Newly diagnosed population annually
0.40 million people
Global SLE prevalence (per 100 000 persons)
43.7
15.87 to 108.92
Affected population
3.41 million people
Further pooled results
SLE incidence by sex
Newly diagnosed annually Women 0.34 million people · Men 0.06 million people
SLE prevalence by sex
Affected population Women 3.04 million people · Men 0.36 million people
Original publication
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