Vasculitis & polymyalgia rheumatica
Giant cell arteritis in patients with systemic sclerosis: a case series
Authors' conclusion
Glucocorticoid treatment for GCA did not precipitate SRC, even in those with prior history of SRC.
Study context
- Population
- Patients with diagnosis codes for both systemic sclerosis (SSc) and giant cell arteritis (GCA), diagnosed by a rheumatologist, January 1, 1996 to December 31, 2020all female
- Participants
- 8 patients
- Outcome
- Description of GCA/SSc overlap cases
Methodological detailssingle-institution
- Single-institution
Main finding
As reported in the abstract
- Fully met both ACR/EULAR classification criteria sets
- 7
- Fulfilled GCA criteria and had 8/9 points for SSc criteria plus oesophagogram consistent with SSc
- 1
- Previous history of scleroderma renal crisis (SRC) prior to GC initiation for GCA
- 3
- Episodes of SRC following initiation of GCs
- 0
- Treated with tocilizumab
- 3
- Remained on tocilizumab and in remission
- 1
Observational data: associations, not effects.
Safety
- Diverticular perforation on tocilizumab requiring colonic resection and colostomy
- 1
- Discontinued tocilizumab after a medication-unrelated complication
- 1
Original publication
Giant cell arteritis in patients with systemic sclerosis: a case series. Clin Exp Rheumatol. Published 14 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →