Geriatric nutritional risk index as the prognostic factor in older patients with fragility hip fractures
Authors' conclusion
We showed that older age, male sex, a lower GNRI score, comorbidities, and a lower BI are risk factors for mortality following FHFs. GNRI is a novel and simple predictor of long-term survival after FHFs.
Study context
- Population
- Japanese patients over 60 years with fragility hip fractures (FHFs); mean age 82 years (range 60–101)mean follow-up 4.0 years
- Participants
- 623 participants
- Exposure
- Geriatric nutritional risk index (GNRI) risk categories
- Outcome
- Long-term mortality after FHFs (GNRI as risk factor)
Methodological detailsmultivariate Cox proportional hazard analysis
- Multivariate Cox proportional hazard analysis
Main finding
As reported in the abstract
Mortality, multivariate Cox analysis
- Lower GNRI score, HR
- 0.96
- Older age, HR
- 1.04
- Male sex, HR
- 1.96
- Malignancy, HR
- 2.51
- Ischemic heart disease, HR
- 2.24
- Revised Hasegawa dementia scale ≤ 20, HR
- 1.64
- No use of active vitamin D3 on admission, HR
- 0.46
- Lower Barthel index on admission, HR
- 1.00
- Lower Barthel index at discharge, HR
- 0.99
- Major and moderate GNRI risk: significantly lower overall survival
- p < 0.001
Observational data: associations, not effects.
Further findings
Overall survival after FHFs · 1 and 5 years
- 1 year
- 91%
- 5 years
- 62%
Incidence of secondary FHFs · 1 and 5 years
- 1 year
- 4%
- 5 years
- 22%
Lower body mass index (BMI) as prognostic factor for secondary FHFs
- HR (p = 0.004)
- 0.88
Original publication
Geriatric nutritional risk index as the prognostic factor in older patients with fragility hip fractures. Osteoporos Int. Published 17 April 2023. doi:10.
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