Spondyloarthritis & psoriatic arthritis
Frequency of irritable bowel syndrome in spondyloarthritis: a multicentric cross-sectional study and meta-analysis
Authors' conclusion
The prevalence of IBS symptoms was high in the ax-SpA population and should therefore be considered in the presence of gastrointestinal disorders.
Study context
- Population
- Consecutive patients with axSpA treated with biologics, five rheumatology departments
- Participants
- 500 patients
- Outcome
- Prevalence of IBS symptoms (Rome IV criteria)
Methodological detailsmulticentric, consecutive patients, PRISMA guidelines
- Multicentric
- Consecutive patients
- PRISMA guidelines
Pooled result
As reported in the abstract
IBS symptoms
Axial spondyloarthritis (ax-SpA)
25%
124 of 500
Further pooled results
| Outcome | Values | OR (CI) | |
|---|---|---|---|
| IBS in SpAvs healthy controls (meta-analysis of five studies)Five studies | SpA 323/7292 events · Healthy controls 484/35587 events | 1.59 (1.05–2.40) | |
| 0.512Odds ratio (log scale) |
| Outcome | Values |
|---|---|
| Prevalence of IBS in SpA (literature review) | SpA 15.4% (interval 8.8%–23.3%) |
Factors associated with irritable bowel syndrome (IBS) symptoms (multivariate model)
- Risk of IBS associated with anxiety and physical inactivity
Factors associated with IBS symptoms (univariate)
- Female gender, unemployment, higher Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), worse BASFI, multiple lines of biologics, FM, anxiety, depression and lower physical activity associated with IBS symptoms
Original publication
Frequency of irritable bowel syndrome in spondyloarthritis: a multicentric cross-sectional study and meta-analysis. RMD Open. Published 12 January 2024. doi:10.
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