Gout & crystal arthritis

Filling gaps in female gout: a cross-sectional study of comorbidities in 192 037 hospitalised patients

RMD OpenPublished Cross-sectional study

Authors' conclusion

A nationwide analysis of inpatients with gout in 2005-2015 confirms a different comorbidity profile between men and women.

Study context

Population
Hospitalisations in people with gout (ICD-9 coding), public and private Spanish hospitals, 2005 to 2015
Participants
192,037 hospitalisations
Exposure
Women vs men hospitalised with gout
Outcome
Prevalence of comorbidities in women vs men hospitalised with gout
Methodological detailsobservational, multicentre, multivariable logistic regression, decision tree algorithm
  • Observational
  • Multicentre
  • Multivariable logistic regression
  • Decision tree algorithm

Main finding

As reported in the abstract

Comorbidities by sex
  • Obesity, dyslipidaemia, CKD, diabetes mellitus, HF, dementia, urinary tract infection and concurrent rheumatic disease more common in women
  • Female sex strongly associated with increasing age, HF, obesity, urinary tract infection and diabetes mellitus
  • Male sex associated with obstructive respiratory diseases, coronary disease and peripheral vascular disease

Observational data: associations, not effects.

Further findings

Age · women significantly older

P < 0.001

Decision tree algorithm predicting sex from age and comorbidities

Accuracy
74.4%

Original publication

Filling gaps in female gout: a cross-sectional study of comorbidities in 192 037 hospitalised patients. RMD Open. Published 9 June 2023. doi:10.1136/rmdopen-2023-003191

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