Exploring perceptions of using preference elicitation methods to inform clinical trial design in rheumatology: A qualitative study and OMERACT collaboration
Authors' conclusion
Our findings allowed us to consider the potential applications of patient preferences in trial design according to stakeholders within rheumatology who are involved in the trial process.
Study context
- Population
- Patients with rheumatic diseases and rheumatology clinicians/researchers
- Participants
- 17 vs 9
- Comparison
- Patients vs Clinicians/researchers
- Patientsn = 17
- Clinicians/researchersn = 9
- Outcome
- Stakeholder perceptions of using preference elicitation methods to inform judgements when designing clinical trials in rheumatology
Methodological details1-on-1 semi-structured interviews, purposive and snowball sampling, thematic analysis, OMERACT collaboration, Interviews via Zoom, audio-recorded and transcribed; pre-interview video and document provided
- 1-on-1 semi-structured interviews
- Purposive and snowball sampling
- Thematic analysis
- OMERACT collaboration
- Interviews via Zoom, audio-recorded and transcribed; pre-interview video and document provided
Main finding
As reported in the abstract
Themes: overall perceptions, barriers and facilitators
- Patients and clinicians/researchers generally agreed that preference elicitation studies can improve clinical trial design, but many considerations are required around preference heterogeneity and feasibility
- Key barrier: additional resources and expertise required to measure and incorporate preferences effectively in trial design
- Key facilitators: guidance on using preference elicitation to inform trial design; role of external decision-makers in developing such guidance; leveraging the movement towards patient engagement in research
- Data and inductive thematic saturation achieved within each group
Original publication
Exploring perceptions of using preference elicitation methods to inform clinical trial design in rheumatology: A qualitative study and OMERACT collaboration. Semin Arthritis Rheum. Published 3 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →