Examining Rehabilitation Dose in Adults With Rheumatoid Arthritis: Association With Baseline Factors and Change in Clinical Outcomes
Authors' conclusion
Using real-world data, this study supports a higher rehabilitation dose to improve physical function in adults with RA.
Study context
- Population
- Adults with rheumatoid arthritis (RA) with a new episode of rehabilitation, National Databank for Rheumatic Diseases registrynew rehabilitation episode
- Participants
- 1,381 adults
- Exposure
- High or medium vs low rehabilitation dose
- Outcome
- Change in physical function (HAQ), pain (VAS) and fatigue (VAS), categorised as improved, no change or worsened
- Follow-up
- 6 months
Methodological detailsregistry-based (National Databank for Rheumatic Diseases), proportional odds logistic regression, adjusted for potential confounders
- Registry-based (National Databank for Rheumatic Diseases)
- Proportional odds logistic regression
- Adjusted for potential confounders
Main finding
As reported in the abstract
Favourable change in physical function (HAQ)
High dose vs Low doseEstimate (95% CI)
Unadjusted
OR 1.51(1.14–1.98)
Adjusted model
aOR 1.41(1.03–1.92)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Favourable change in pain (VAS) · 6 monthsHigh dosevs Low doseUnadjusted | 1.44 (1.06–1.96) | |
| Favourable change in fatigue (VAS) · 6 monthsHigh dosevs Low doseUnadjusted | 1.45 (1.06–1.99) | |
| 0.512Odds ratio (log scale) |
Favourable change in pain (VAS) · 6 months
- Association did not persist in adjusted models
Favourable change in fatigue (VAS) · 6 months
- Association did not persist in adjusted models
Baseline factors associated with higher rehabilitation dose
- Worse baseline physical function, aOR
- 1.29 (1.04-1.60) (95% CI)
- Baseline pain, aOR
- 1.04 (0.99-1.10) (95% CI)
- Baseline fatigue, aOR
- 0.98 (0.93-1.03) (95% CI)
Original publication
Examining Rehabilitation Dose in Adults With Rheumatoid Arthritis: Association With Baseline Factors and Change in Clinical Outcomes. Arthritis Care Res (Hoboken). Published 18 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →