Spondyloarthritis & psoriatic arthritis

Evaluation of Financial and Nonfinancial Conflicts of Interest and Quality of Evidence Underlying Psoriatic Arthritis Clinical Practice Guidelines: Analysis of Personal Payments From Pharmaceutical Companies and Authors’ Self‐Citation Rate in Japan and the United States

Arthritis Care Res (Hoboken)Published Retrospective cross-sectional analysis

Study context

Population
All authors of psoriatic arthritis (PsA) clinical practice guideline (CPGs) issued by the Japanese Dermatological Association (JDA) and American College of Rheumatology (ACR), Japan and the US, 2016–2018
Participants
23 vs 25
Exposure
PsA CPG authors in Japan vs the US
  • JDAn = 23
  • ACRn = 25
Outcome
Financial and nonfinancial conflicts of interest (COI) of PsA CPG authors; quality of evidence and strength of recommendations
Follow-up
2016–2018
Methodological detailspayment data from major Japanese pharmaceutical companies and US Open Payments Database, 2016–2018
  • Payment data from major Japanese pharmaceutical companies and US Open Payments Database, 2016–2018

Main finding

As reported in the abstract

CPG authors receiving at least 1 payment from pharmaceutical companies
GroupValueCombined total payment
Japan91.3%$3,335,413
US84.0%$4,081,629

Value

Japan91.3%
US84.0%

Combined total payment

Japan$3,335,413
US$4,081,629

Observational data: associations, not effects.

Further findings

Authors with undisclosed financial COI

Undisclosed financial COI worth JDA $474,663 · ACR $218,501

Recommendations supported by low or very low quality of evidence

  • 3-year combined payment per author: Japan mean 145,018 (SD 114,302) $
  • 3-year combined payment per author: US mean 162,825 (SD 259,670) $
  • Citations with at least 1 CPG author relative to total citations (self-citation): Japan 3.4%
  • Citations with at least 1 CPG author relative to total citations (self-citation): US 33.6%

Original publication

Evaluation of Financial and Nonfinancial Conflicts of Interest and Quality of Evidence Underlying Psoriatic Arthritis Clinical Practice Guidelines: Analysis of Personal Payments From Pharmaceutical Companies and Authors’ Self‐Citation Rate in Japan and the United States. Arthritis Care Res (Hoboken). Published 14 January 2023. doi:10.1002/acr.25032

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