EULAR /American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia
An erratum to this article was published (Arthritis Rheumatol, Nov 2026 ↗)
Authors' conclusion
EULAR/ACR risk stratification criteria have been developed for people with arthralgia in secondary care who are considered at risk for RA.
Study context
- Population
- Persons presenting with arthralgia considered at risk of rheumatoid arthritis (RA) (clinically suspect arthralgia and autoantibody-positive arthralgia)
- Participants
- 2,293 persons10 arthralgia cohorts
- Comparison
- Clinical and serologic criteria vs Criteria with magnetic resonance imaging (MRI)
- Outcome
- Progression to clinically apparent inflammatory arthritis (IA)
- Follow-up
- 1 year
Methodological detailsjoint EULAR/ACR expert committee, 10 arthralgia cohorts
- Joint EULAR/ACR expert committee
- 10 arthralgia cohorts
Performance
As reported in the abstract
Discrimination for IA development
| Test or model | AUC | Sensitivity and specificity |
|---|---|---|
| Clinical and serologic criteria | 0.80 (95% CI 0.77-0.83) | — not stated in the abstract |
| Criteria with MRI | 0.87 (95% CI 0.82-0.90) | >75% |
AUC
Clinical and serologic criteria0.80 (95% CI 0.77-0.83)
Criteria with MRI0.87 (95% CI 0.82-0.90)
Sensitivity and specificity
Clinical and serologic criteria— not stated in the abstract
Criteria with MRI>75%
— not stated in the abstract
Secondary outcomes
| Outcome | Criteria with MRI |
|---|---|
| RA development (2010 EULAR/ACR criteria) · 1 year | |
| AUC | 0.93 (95% CI 0.90-0.97) |
Original publication
EULAR /American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia. Arthritis Rheumatol. Published 8 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →