ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease developed by the task force for connective tissue disease-associated interstitial lung disease of the European Respiratory Society (ERS) and the European Alliance of Associations for Rheumatology (EULAR) Endorsed by the European Reference Network on rare respiratory diseases (ERN-LUNG)
Methodological detailsGRADE methodology, PICO questions, narrative questions, Evidence to Decision framework
- GRADE methodology
- PICO questions
- Narrative questions
- Evidence to Decision framework
Recommendations
As issued by the authors
Recommendations for 25 PICO and 28 narrative questions on interstitial lung disease (ILD) in SSc, rheumatoid arthritis (RA), IIM, Sjögren disease (SjD), systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD)
Insufficient evidence to support recommendations in four narrative questions (screening and risk of ILD progression in MCTD, SjD and SLE) and one PICO question (pirfenidone in CTD-ILD other than RA-ILD)
Screening, diagnostic, monitoring and treatment algorithms developed from the recommendations and usual clinical practice
Original publication
ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease developed by the task force for connective tissue disease-associated interstitial lung disease of the European Respiratory Society (ERS) and the European Alliance of Associations for Rheumatology (EULAR) Endorsed by the European Reference Network on rare respiratory diseases (ERN-LUNG). Ann Rheum Dis. Published 4 September 2025. doi:10.
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