Lupus & antiphospholipid syndrome

ERN ReCONNET–SLICC–SLEuro expert consensus on the therapeutic management of rare systemic lupus erythematosus manifestations

Lancet RheumatolPublished Expert consensus statement

Methodological detailsinternational taskforce, multistep process
  • International taskforce
  • Multistep process

Recommendations

As issued by the authors

  1. Systemic lupus erythematosus (SLE) enteritis and pancreatitis: HCQ, GC, and CYC or MMF.

  2. Rare lung conditions such as pneumonitis: CYC if severe, MMF if not severe.

  3. Myocarditis: HCQ, GC, and CYC or MMF, based on severity.

  4. CNS manifestations: HCQ, GC, and CYC or MMF were common choices.

  5. Rare skin manifestations: preferred HCQ plus GC with anifrolumab or MMF.

Original publication

ERN ReCONNET–SLICC–SLEuro expert consensus on the therapeutic management of rare systemic lupus erythematosus manifestations. Lancet Rheumatol. Published 23 May 2025. doi:10.1016/s2665-9913(25)00063-3

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