Effects of a personalized exercise program on physical function in older patients with rheumatoid arthritis at high risk of sarcopenia: results of a randomized controlled trial
Primary result · Change in SPPB total score from baselineResult — go to the resultDifference 0.2 points 95% CI −0.1 to 0.5Authors' conclusion
The 16-week personalized exercise therapy did not improve the total SPPB scores.
Study context
- Population
- Patients with rheumatoid arthritis (RA) aged 60–85 years at risk of sarcopenia134 initiated intervention
- Participants
- 140 patients
- Comparison
- 16-week personalized exercise program plus nutritional guidance and standard care vs nutritional guidance and standard care only
- Interventionn = 69
- Controln = 65reference
- Primary endpoint
- Change in total Short Physical Performance Battery (SPPB) score from baseline
- Follow-up
- Week 16
Methodological detailssingle-centre, parallel-group, two-arm, superiority
- Single-centre
- Parallel-group
- Two-arm
- Superiority
Primary result
Change in SPPB total score from baseline
Difference
0.2 points
95% CI −0.1 to 0.5
P = 0.206
Change by group
Intervention
+ 0.4
points
Control
+ 0.2
points
Interventionvs Control
difference 0.2 points (95% CI −0.1 to 0.5); P = 0.206
As reported in the abstract
Secondary outcomes
Chair-stand test, grip strength and mental component score · week 16
- Tendency for improvement
Original publication
Effects of a personalized exercise program on physical function in older patients with rheumatoid arthritis at high risk of sarcopenia: results of a randomized controlled trial. Arthritis Res Ther. Published 6 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →