Spondyloarthritis & psoriatic arthritis
Early Diagnosis of Axial Spondyloarthritis Is Associated With Less Long‐Term Spinal Structural Damage: A Longitudinal Analysis of the Swiss Clinical Quality Management in Rheumatic Diseases Registry
Main finding · Long-term mSASSSResult — go to the resultDifference −3.85 mSASSS units 95% CI −7.28 to −0.42Authors' conclusion
Early diagnosis of axSpA is associated with lower long-term spinal structural damage.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) with at least two sets of spinal radiographs, 2004–2024, Swiss Clinical Quality Management registry, under standard of care treatment1,181 sets of radiographs
- Participants
- 376 patients
- Exposure
- Early axSpA vs established axSpA
- Early axSpAn = 138
- Established axSpAn = 238reference
- Outcome
- Longitudinal spinal radiographic progression (modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS)) from diagnosis
Methodological detailsregistry-based, longitudinal, four-parametric logistic model
- Registry-based
- Longitudinal
- Four-parametric logistic model
Main finding
Long-term mSASSS
Difference
−3.85 mSASSS units
95% CI −7.28 to −0.42
Early axSpAvs Established axSpA
difference −3.85 mSASSS units (95% CI −7.28 to −0.42)
As reported in the abstract
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Early Diagnosis of Axial Spondyloarthritis Is Associated With Less Long‐Term Spinal Structural Damage: A Longitudinal Analysis of the Swiss Clinical Quality Management in Rheumatic Diseases Registry. Arthritis Rheumatol. Published 18 September 2026. doi:10.
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