Lupus & antiphospholipid syndrome
Does Higher Quality of Care in Systemic Lupus Erythematosus Improve Quality of Life?
Authors' conclusion
High QOC at baseline and the number of years with high QOC are not associated with MCID improvement in SF-36 scores and nonroutine HCU on follow-up. High QOC, as determined by currently defined criteria, serves as a surrogate of greater disease activity, morbidity, and nonroutine HCU.
Study context
- Population
- Participants with SLE from the Lupus Outcomes Study sample
- Participants
- 814 participants
- Exposure
- Higher vs lower quality of care at baseline
- Outcome
- Association of high QOC (13 self-reported quality indices) with quality of life (QOL) (SF-36) and nonroutine health care use
- Follow-up
- 2 years
Methodological detailsLupus Outcomes Study sample, annual interviews, univariate and multivariate regression, logistic regression
- Lupus Outcomes Study sample
- Annual interviews
- Univariate and multivariate regression
- Logistic regression
Main finding
As reported in the abstract
MCID improvement in SF-36 scores · follow-up (2 years)
- Quality of care (QOC) and the number of years in high QOC were not predictive of minimal clinically important difference (MCID) improvements in SF-36 scores at follow-up; driven by baseline SF-36 scores, disease activity and nonroutine health care use (HCU)
Observational data: associations, not effects.
Further findings
SF-36 domains at baseline (univariate)
- Higher QOC associated with worse SF-36 domain scores, mediated by comorbidities and high disease activity
Emergency room (ER) visits and hospitalizations · follow-up
- Not predicted by QOC; disease activity, damage and GC dose were significant predictors
Original publication
Does Higher Quality of Care in Systemic Lupus Erythematosus Improve Quality of Life? Arthritis Care Res (Hoboken). Published 1 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →