DISH as a marker for incident diabetes mellitus in cardiovascular disease patients
Main finding · Incident T2DMResult — go to the resultIncidence rate ratio 1.47 95% CI 1.03–2.06Authors' conclusion
DISH is associated with higher rates of incident T2DM in cardiovascular disease patients, independent of accepted risk markers.
Study context
- Population
- CVD patients without diabetes
- Participants
- 3,395 patients
- Exposure
- DISH vs no DISH
- DISHn = 263
- Outcome
- Incident T2DM
Methodological detailsSecond Manifestation of ARTerial disease cohort, multivariate analyses
- Second Manifestation of ARTerial disease cohort
- Multivariate analyses
Main finding
As reported in the abstract
median follow-up 11.1 years (IQR: 7.1-15.2)
Incidence rate ratio
1.47
95% CI 1.03–2.06
By group
DISHvs No-DISH
IRR 1.47 (95% CI 1.03–2.06)
- Patients who developed T2DM
- 317
Observational data: associations, not effects.
Further findings
| Outcome | IRR (95% CI) | |
|---|---|---|
| Incident T2DM, DISH with most extensive ossificationDISH (most extensive ossification)vs No-DISH | 2.01 (1.15–3.29) | |
| 0.20.5125Incidence rate ratio (log scale) |
Number needed to screen for T2DM over 11.1 years · median 11.1 years
- Screen-detected DISH
- 7
- Overweight
- 8
- Obesity
- 5
- Hypertension
- 9
- Hyperlipidaemia
- 13
Original publication
DISH as a marker for incident diabetes mellitus in cardiovascular disease patients. Rheumatology (Oxford). Published 27 May 2025. doi:10.
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