Development of START, a novel multimedia-based symptom appraisal tool for autoimmune rheumatic diseases
Authors' conclusion
A novel multimedia-based symptom appraisal tool for ARDs was developed, which addresses the limitations of existing tools and exhibited promising sensitivity and specificity in detecting patients with known ARDs.
Study context
- Population
- Established ARD cases, non-ARD patients and healthy controls
- Participants
- 145 / 133 / 155
- Comparison
- START symptom appraisal tool in ARD cases vs non-ARD controls
- Autoimmune rheumatic diseases (ARDs)n = 145
- Non-ARDsn = 133reference
- Healthy controlsn = 155reference
- Outcome
- Sensitivity, specificity and test-retest reliability of START in detecting patients with known ARDs
Methodological detailstool development, expert panel consensus, cognitive debriefing interviews, pilot test
- Tool development
- Expert panel consensus
- Cognitive debriefing interviews
- Pilot test
Performance
As reported in the abstract
Detection of any ARD by START
| Test or model | Sensitivity | Specificity | Test-retest reliability |
|---|---|---|---|
| START | 86.2% | 80.9% | 0.789 |
START
Sensitivity86.2%
Specificity80.9%
Test-retest reliability0.789
Further findings
Tool development: manifestations reaching expert consensus for content validity
- Manifestations identified
- 59
- Reached expert consensus
- 33
- Removed (non-specific or late features)
- 26
- Final items after grouping
- 19
- Patients in cognitive debriefing interviews (CDIs)
- 36
Original publication
Development of START, a novel multimedia-based symptom appraisal tool for autoimmune rheumatic diseases. Rheumatology (Oxford). Published 25 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →