Lupus & antiphospholipid syndrome
Development of an instrument to predict proliferative histological class in lupus nephritis based on clinical and laboratory data
Authors' conclusion
Rheumatologists and nephrologists with experience in treating LN generated evaluations that correlated weakly with kidney biopsy.
Study context
- Population
- SLE patients (SLICC 2012 classification) who underwent kidney biopsy between 2010 and 2017; mean age 33 ± 10.3 years, disease duration 11.5 ± 6.7 years
- Participants
- 80 patients
- Exposure
- Rheumatologists and nephrologists vs Instrument
- Outcome
- Agreement between evaluators (rheumatologists and nephrologists) and kidney biopsy on histological class
Methodological detailsdecision tree (chi-square interaction detector), logistic regression
- Decision tree (chi-square interaction detector)
- Logistic regression
Main finding
As reported in the abstract
Level of agreement between the evaluators and kidney biopsy was poor (global K ± SE)
0.364 ± 0.029
p < .001
Observational data: associations, not effects.
Original publication
Development of an instrument to predict proliferative histological class in lupus nephritis based on clinical and laboratory data. Lupus. Published 2 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →