Determining patient preferences for the medical management of osteoporosis using conjoint analysis
Authors' conclusion
While about 60% of patients prioritized efficacy when selecting an osteoporosis therapy, the remaining 40% valued other factors more highly. Furthermore, individual patient characteristics and clinical factors did not reliably predict patient decision making
Study context
- Population
- Osteoporosis patients at an academic medical centercompleted the survey
- Participants
- 304 patients
- Outcome
- Relative importance score of 6 osteoporosis medication attributes (higher = greater relative importance in decision-making)
Methodological detailsconjoint analysis, latent class analysis, logistic regression, single academic medical center, online survey
- Conjoint analysis
- Latent class analysis
- Logistic regression
- Single academic medical center
- Online survey
Main finding
As reported in the abstract
Relative importance of medication attributes in decision making
- Efficacy at preventing hip fractures
- 31.0%
- Mode of administration
- 17.5%
- Risk of serious side effects
- 16.6%
- Dose frequency
- 13.9%
- Efficacy at preventing spine fractures
- 12.5%
- Risk of non-serious side effects
- 8.4%
Observational data: associations, not effects.
Further findings
Prioritised medication efficacy as top factor (latent class)
- Proportion of cohort prioritising efficacy
- 60.9%
Factors associated with prioritising efficacy
- Being a college graduate, stronger beliefs on necessity of osteoporosis medications, and never having used osteoporosis medicines were the only associated factors
Original publication
Determining patient preferences for the medical management of osteoporosis using conjoint analysis. Osteoporos Int. Published 18 September 2023. doi:10.
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