Spondyloarthritis & psoriatic arthritis
Comparison of patients with axial psoriatic arthritis (PsA) and patients with axial spondyloarthritis (axSpA) and concomitant psoriasis: an analysis of the German register RABBIT-SpA
Authors' conclusion
AxPsA differs from axSpA+pso in its clinical manifestations, irrespective of whether axPsA is defined clinically or by imaging.
Study context
- Population
- Patients with PsA and axSpA in the German register RABBIT-SpA1,428 axSpA
- Exposure
- Axial PsA vs axSpA with concomitant psoriasis
- axPsAn = 359
- axSpA+pson = 181reference
- Outcome
- Demographic and disease-specific parameters of axPsA vs axSpA+pso
Methodological detailsprospective longitudinal, register-based (RABBIT-SpA)
- Prospective longitudinal
- Register-based (RABBIT-SpA)
Main finding
As reported in the abstract
- AxSpA+pso differed from axPsA regardless of whether clinical or imaging definition was used
- axPsA patients older, more often female and less often HLA-B27+
- Peripheral manifestations more often in axPsA than axSpA+pso
- Uveitis and inflammatory bowel disease more common in axSpA+pso
- Burden of disease (patient global, pain, physician global) similar in axPsA and axSpA+pso
Observational data: associations, not effects.
Further findings
- Psoriasis among axSpA patients — axSpA+pso
- 13%
- Psoriasis among axSpA patients: 181/1428 axSpA patients
- Axial involvement among PsA patients: PsA 26%
- Axial involvement among PsA patients: of 1395 PsA patients
- Axial manifestation of PsA, clinical definition: PsA 21%
- Axial manifestation of PsA, imaging definition: PsA 14%
Burden of disease (patient global, pain, physician global)
- Similar among axPsA and axSpA+pso patients
Original publication
Comparison of patients with axial PsA and patients with axSpA and concomitant psoriasis: an analysis of the German register RABBIT-SpA. RMD Open. Published 10 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →